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Tunable regulation of CREB DNA binding activity couples genotoxic stress response and metabolism
cAMP response element binding protein (CREB) is a key regulator of glucose metabolism and synaptic plasticity that is canonically regulated through recruitment of transcriptional coactivators. Here we show that phosphorylation of CREB on a conserved cluster of Ser residues (the ATM/CK cluster) by th...
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| Udgivet i: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5175338/ https://ncbi.nlm.nih.gov/pubmed/27431323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw643 |
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