Essential role of BCL9-2 in the switch between β-catenin's adhesive and transcriptional functions

β-Catenin controls both cadherin-mediated cell adhesion and activation of Wnt target genes. We demonstrate here that the β-catenin-binding protein BCL9-2, a homolog of the human proto-oncogene product BCL9, induces epithelial-mesenchymal transitions of nontransformed cells and increases β-catenin-de...

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Bibliografiske detaljer
Main Authors: Brembeck, Felix H., Schwarz-Romond, Thomas, Bakkers, Jeroen, Wilhelm, Sabine, Hammerschmidt, Matthias, Birchmeier, Walter
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2004
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC517514/
https://ncbi.nlm.nih.gov/pubmed/15371335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.317604
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