Essential role of BCL9-2 in the switch between β-catenin's adhesive and transcriptional functions

β-Catenin controls both cadherin-mediated cell adhesion and activation of Wnt target genes. We demonstrate here that the β-catenin-binding protein BCL9-2, a homolog of the human proto-oncogene product BCL9, induces epithelial-mesenchymal transitions of nontransformed cells and increases β-catenin-de...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Brembeck, Felix H., Schwarz-Romond, Thomas, Bakkers, Jeroen, Wilhelm, Sabine, Hammerschmidt, Matthias, Birchmeier, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517514/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15371335/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.317604
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