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Essential role of BCL9-2 in the switch between β-catenin's adhesive and transcriptional functions
β-Catenin controls both cadherin-mediated cell adhesion and activation of Wnt target genes. We demonstrate here that the β-catenin-binding protein BCL9-2, a homolog of the human proto-oncogene product BCL9, induces epithelial-mesenchymal transitions of nontransformed cells and increases β-catenin-de...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC517514/ https://ncbi.nlm.nih.gov/pubmed/15371335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.317604 |
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