Involvement of CD14, Toll-Like Receptors 2 and 4, and MyD88 in the Host Response to the Fungal Pathogen Cryptococcus neoformans In Vivo

The major capsular polysaccharide of Cryptococcus neoformans, glucuronoxylomannan (GXM), is recognized by Toll-like receptor 2 (TLR2), TLR4, and CD14. In these studies, mice deficient in CD14, TLR2, TLR4, and the TLR-associated adaptor protein, MyD88, were utilized to investigate the contribution of...

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Autors principals: Yauch, Lauren E., Mansour, Michael K., Shoham, Shmuel, Rottman, James B., Levitz, Stuart M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC517466/
https://ncbi.nlm.nih.gov/pubmed/15322035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.9.5373-5382.2004
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