Receptor-Mediated Clearance of Cryptococcus neoformans Capsular Polysaccharide In Vivo

Cryptococcus neoformans capsular glucuronoxylomannan (GXM) is shed during cryptococcosis and taken up by macrophages. The roles of the putative GXM receptors CD14, CD18, Toll-like receptor 2 (TLR2), and TLR4 in GXM clearance from serum and deposition in the liver and spleen in receptor-deficient mic...

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Bibliographic Details
Main Authors: Yauch, Lauren E., Mansour, Michael K., Levitz, Stuart M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307074/
https://ncbi.nlm.nih.gov/pubmed/16299344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.8429-8432.2005
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