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Receptor-Mediated Clearance of Cryptococcus neoformans Capsular Polysaccharide In Vivo

Cryptococcus neoformans capsular glucuronoxylomannan (GXM) is shed during cryptococcosis and taken up by macrophages. The roles of the putative GXM receptors CD14, CD18, Toll-like receptor 2 (TLR2), and TLR4 in GXM clearance from serum and deposition in the liver and spleen in receptor-deficient mic...

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Autori principali: Yauch, Lauren E., Mansour, Michael K., Levitz, Stuart M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307074/
https://ncbi.nlm.nih.gov/pubmed/16299344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.8429-8432.2005
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