The P Domain of the P0 Protein of Plasmodium falciparum Protects against Challenge with Malaria Parasites

Monoclonal antibodies (MAbs) specific for the P domain of the Plasmodium falciparum P0 phosphoriboprotein (PfP0) blocked the invasion of RBCs by P. falciparum. Vaccination with this P-domain peptide protected mice upon malaria parasite challenge. The absolute specificity of the MAbs and the PfP0 P p...

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Main Authors: Rajeshwari, K., Patel, Kalpesh, Nambeesan, Savithri, Mehta, Monika, Sehgal, Alfica, Chakraborty, Tirtha, Sharma, Shobhona
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC517436/
https://ncbi.nlm.nih.gov/pubmed/15322057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.9.5515-5521.2004
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