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Synchronous hippocampal bursting reveals network excitability defects in an epilepsy gene mutation.

A mutation at the tottering locus (tg, recessive, on chromosome 8) stimulates noradrenergic locus coeruleus axon terminal outgrowth and predisposes the brain to generalized spike-wave epilepsy in the young mouse. In an isolated synaptic circuit studied in vitro, the hyperinnervated mutant hippocampa...

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Bibliografiska uppgifter
Huvudupphovsmän: Helekar, S A, Noebels, J L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1991
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC51741/
https://ncbi.nlm.nih.gov/pubmed/2052555
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