BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo

Deletion of various bone morphogenetic proteins (BMPs) and their downstream Smads in mice have clearly shown that BMP signaling is essential for the formation of primordial germ cells (PGCs). However, the molecular mechanism through which this takes place is still unclear. Here, we demonstrate that...

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Detaylı Bibliyografya
Asıl Yazarlar: de Sousa Lopes, Susana M. Chuva, Roelen, Bernard A.J., Monteiro, Rui M., Emmens, Roul, Lin, Herbert Y., Li, En, Lawson, Kirstie A., Mummery, Christine L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2004
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC517404/
https://ncbi.nlm.nih.gov/pubmed/15289457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.294004
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