MUC13 Interaction with Receptor Tyrosine Kinase HER2 Drives Pancreatic Ductal Adenocarcinoma Progression

Although MUC13, a transmembrane mucin, is aberrantly expressed in pancreatic ductal adenocarcinoma (PDAC) and generally correlates with increased expression of HER2, the underlying mechanism remains poorly understood. Herein, we found that MUC13 co-localizes and interacts with HER2 in PDAC cells (re...

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Publicat a:Oncogene
Autors principals: Khan, Sheema, Sikander, Mohammed, Ebeling, Mara C., Ganju, Aditya, Kumari, Sonam, Yallapu, Murali M., Hafeez, Bilal Bin, Ise, Tomoko, Nagata, Satoshi, Zafar, Nadeem, Behrman, Stephen W., Wan, Jim Y., Ghimire, Hemendra M., Sahay, Peeyush, Pradhan, Prabhakar, Chauhan, Subhash C., Jaggi, Meena
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173450/
https://ncbi.nlm.nih.gov/pubmed/27321183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.218
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