MUC13 Interaction with Receptor Tyrosine Kinase HER2 Drives Pancreatic Ductal Adenocarcinoma Progression

Although MUC13, a transmembrane mucin, is aberrantly expressed in pancreatic ductal adenocarcinoma (PDAC) and generally correlates with increased expression of HER2, the underlying mechanism remains poorly understood. Herein, we found that MUC13 co-localizes and interacts with HER2 in PDAC cells (re...

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Vydáno v:Oncogene
Hlavní autoři: Khan, Sheema, Sikander, Mohammed, Ebeling, Mara C., Ganju, Aditya, Kumari, Sonam, Yallapu, Murali M., Hafeez, Bilal Bin, Ise, Tomoko, Nagata, Satoshi, Zafar, Nadeem, Behrman, Stephen W., Wan, Jim Y., Ghimire, Hemendra M., Sahay, Peeyush, Pradhan, Prabhakar, Chauhan, Subhash C., Jaggi, Meena
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173450/
https://ncbi.nlm.nih.gov/pubmed/27321183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.218
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