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Progress of endocytic CHRN to autophagic degradation is regulated by RAB5-GTPase and T145 phosphorylation of SH3GLB1 at mouse neuromuscular junctions in vivo

Endocytosed nicotinic acetylcholine receptors (CHRN) are degraded via macroautophagy/autophagy during atrophic conditions and are accompanied by the autophagic regulator protein SH3GLB1. The present study addressed the functional role of SH3GLB1 on CHRN trafficking and its implementation. We found a...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Autophagy
Päätekijät: Wild, Franziska, Khan, Muzamil Majid, Straka, Tatjana, Rudolf, Rüdiger
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173261/
https://ncbi.nlm.nih.gov/pubmed/27715385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1234564
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