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Identification of Post-Transcriptional Modulators of Breast Cancer Transcription Factor Activity Using MINDy

We have recently identified transcription factors (TFs) that are key drivers of breast cancer risk. To better understand the pathways or sub-networks in which these TFs mediate their function we sought to identify upstream modulators of their activity. We applied the MINDy (Modulator Inference by Ne...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Campbell, Thomas M., Castro, Mauro A. A., Ponder, Bruce A. J., Meyer, Kerstin B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173250/
https://ncbi.nlm.nih.gov/pubmed/27997592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168770
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