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Essential Genes Embody Increased Mutational Robustness to Compensate for the Lack of Backup Genetic Redundancy

Genetic robustness is a hallmark of cells, occurring through many mechanisms and at many levels. Essential genes lack the common robustness mechanism of genetic redundancy (i.e., existing alongside other genes with the same function), and thus appear at first glance to leave cells highly vulnerable...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cohen, Osher, Oberhardt, Matthew, Yizhak, Keren, Ruppin, Eytan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173180/
https://ncbi.nlm.nih.gov/pubmed/27997585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168444
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