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Metabolic modeling of endosymbiont genome reduction on a temporal scale

A fundamental challenge in Systems Biology is whether a cell-scale metabolic model can predict patterns of genome evolution by realistically accounting for associated biochemical constraints. Here, we study the order in which genes are lost in an in silico evolutionary process, leading from the meta...

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Main Authors: Yizhak, Keren, Tuller, Tamir, Papp, Balázs, Ruppin, Eytan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094061/
https://ncbi.nlm.nih.gov/pubmed/21451589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.11
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