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Metabolic modeling of endosymbiont genome reduction on a temporal scale

A fundamental challenge in Systems Biology is whether a cell-scale metabolic model can predict patterns of genome evolution by realistically accounting for associated biochemical constraints. Here, we study the order in which genes are lost in an in silico evolutionary process, leading from the meta...

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Detalhes bibliográficos
Main Authors: Yizhak, Keren, Tuller, Tamir, Papp, Balázs, Ruppin, Eytan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094061/
https://ncbi.nlm.nih.gov/pubmed/21451589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.11
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