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Metabolic modeling of endosymbiont genome reduction on a temporal scale

A fundamental challenge in Systems Biology is whether a cell-scale metabolic model can predict patterns of genome evolution by realistically accounting for associated biochemical constraints. Here, we study the order in which genes are lost in an in silico evolutionary process, leading from the meta...

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Detalles Bibliográficos
Autores principales: Yizhak, Keren, Tuller, Tamir, Papp, Balázs, Ruppin, Eytan
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094061/
https://ncbi.nlm.nih.gov/pubmed/21451589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.11
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