WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck

Wolf-Hisrchhorn Syndrome Candidate 1-Like 1 (WHSC1L1) is a protein lysine methyltransferase that is recurrently amplified (8p11.23) in patients with squamous cell carcinoma of the head and neck (SCCHN). In this study, we investigated the oncogenic role of WHSC1L1 in SCCHN. Using immunohistochemistry...

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Udgivet i:Oncotarget
Main Authors: Saloura, Vassiliki, Vougiouklakis, Theodore, Zewde, Makda, Kiyotani, Kazuma, Park, Jae-Hyun, Gao, Guimin, Karrison, Theodore, Lingen, Mark, Nakamura, Yusuke, Hamamoto, Ryuji
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173153/
https://ncbi.nlm.nih.gov/pubmed/27285764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9897
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