Wnt/β-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling

A hallmark of aberrant activation of the Wnt/β-catenin signaling pathway has been observed in most colorectal cancers (CRC), but little is known about the role of non-coding RNAs regulated by this pathway. Here, we found that miR-150 was the most significantly upregulated microRNA responsive to elev...

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Publicado en:Oncotarget
Autores principales: Guo, Yan-Hua, Wang, Lu-Qin, Li, Bin, Xu, Hui, Yang, Jian-Hua, Zheng, Li-Si, Yu, Peng, Zhou, Ai-Dong, Zhang, Yin, Xie, Shu-Juan, Liang, Zi-Rui, Zhang, Chen-Min, Zhou, Hui, Liang-Hu, Qu
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173152/
https://ncbi.nlm.nih.gov/pubmed/27285761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9893
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