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An initial phase of JNK activation inhibits cell death early in the endoplasmic reticulum stress response
Accumulation of unfolded proteins in the endoplasmic reticulum (ER) activates the unfolded protein response (UPR). In mammalian cells, UPR signals generated by several ER membrane resident proteins, including the bifunctional protein kinase endoribonuclease IRE1α, control cell survival and the decis...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5172423/ https://ncbi.nlm.nih.gov/pubmed/27122189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.179127 |
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