Bortezomib initiates endoplasmic reticulum stress, elicits autophagy and death in Echinococcus granulosus larval stage

Cystic echinococcosis (CE) is a worldwide distributed helminthic zoonosis caused by Echinococcus granulosus. Benzimidazole derivatives are currently the only drugs for chemotherapeutic treatment of CE. However, their low efficacy and the adverse effects encourage the search for new therapeutic targe...

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Bibliographic Details
Published in:PLoS One
Main Authors: Nicolao, María Celeste, Loos, Julia A., Rodriguez Rodrigues, Christian, Beas, Viviana, Cumino, Andrea C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560652/
https://ncbi.nlm.nih.gov/pubmed/28817601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181528
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