Glutathione deficiency decreases tissue ascorbate levels in newborn rats: ascorbate spares glutathione and protects.
Glutathione deficiency in newborn rats, produced by administration of L-buthionine-(S,R)-sulfoximine, a transition-state inactivator of gamma-glutamylcysteine synthetase, decreases ascorbate levels of kidney, liver, brain, and lung. These tissues, especially their mitochondria, undergo severe damage...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51724/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2052548/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.11.4656 |
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