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Distinct roles of short and long thymic stromal lymphopoietin isoforms in house dust mite-induced asthmatic airway epithelial barrier disruption

Loss of airway epithelial integrity contributes significantly to asthma pathogenesis. Thymic stromal lymphopoietin (TSLP) may have dual immunoregulatory roles. In inflammatory disorders of the bowel, the long isoform of TSLP (lfTSLP) promotes inflammation while the short isoform (sfTSLP) inhibits in...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Dong, Hangming, Hu, Yahui, Liu, Laiyu, Zou, Mengchen, Huang, Chaowen, Luo, Lishan, Yu, Changhui, Wan, Xuan, Zhao, Haijin, Chen, JiaLong, Xie, Zhefan, Le, Yanqing, Zou, Fei, Cai, Shaoxi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171874/
https://ncbi.nlm.nih.gov/pubmed/27996052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39559
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