Distinct roles of short and long thymic stromal lymphopoietin isoforms in house dust mite-induced asthmatic airway epithelial barrier disruption

Loss of airway epithelial integrity contributes significantly to asthma pathogenesis. Thymic stromal lymphopoietin (TSLP) may have dual immunoregulatory roles. In inflammatory disorders of the bowel, the long isoform of TSLP (lfTSLP) promotes inflammation while the short isoform (sfTSLP) inhibits in...

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Udgivet i:Sci Rep
Main Authors: Dong, Hangming, Hu, Yahui, Liu, Laiyu, Zou, Mengchen, Huang, Chaowen, Luo, Lishan, Yu, Changhui, Wan, Xuan, Zhao, Haijin, Chen, JiaLong, Xie, Zhefan, Le, Yanqing, Zou, Fei, Cai, Shaoxi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171874/
https://ncbi.nlm.nih.gov/pubmed/27996052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39559
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