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Integrative modelling of tumour DNA methylation quantifies the contribution of metabolism
Altered DNA methylation is common in cancer and often considered an early event in tumorigenesis. However, the sources of heterogeneity of DNA methylation among tumours remain poorly defined. Here we capitalize on the availability of multi-platform data on thousands of human tumours to build integra...
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| Publié dans: | Nat Commun |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5171841/ https://ncbi.nlm.nih.gov/pubmed/27966532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13666 |
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