Cargando...

Integrative modelling of tumour DNA methylation quantifies the contribution of metabolism

Altered DNA methylation is common in cancer and often considered an early event in tumorigenesis. However, the sources of heterogeneity of DNA methylation among tumours remain poorly defined. Here we capitalize on the availability of multi-platform data on thousands of human tumours to build integra...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Mehrmohamadi, Mahya, Mentch, Lucas K., Clark, Andrew G., Locasale, Jason W.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171841/
https://ncbi.nlm.nih.gov/pubmed/27966532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13666
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!