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Characterization of the usage of the serine metabolic network in human cancer

The serine, glycine, one carbon (SGOC) metabolic network is implicated in cancer pathogenesis but its general functions are unknown. We carried out a computational reconstruction of the SGOC network and then characterized its expression across thousands of cancer tissues. Pathways including methylat...

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Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Mehrmohamadi, Mahya, Liu, Xiaojing, Shestov, Alexander A, Locasale, Jason W
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317399/
https://ncbi.nlm.nih.gov/pubmed/25456139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.026
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