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Characterization of the usage of the serine metabolic network in human cancer

The serine, glycine, one carbon (SGOC) metabolic network is implicated in cancer pathogenesis but its general functions are unknown. We carried out a computational reconstruction of the SGOC network and then characterized its expression across thousands of cancer tissues. Pathways including methylat...

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Bibliografische gegevens
Gepubliceerd in:Cell Rep
Hoofdauteurs: Mehrmohamadi, Mahya, Liu, Xiaojing, Shestov, Alexander A, Locasale, Jason W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317399/
https://ncbi.nlm.nih.gov/pubmed/25456139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.026
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