Counteracting bone fragility with human amniotic mesenchymal stem cells

The impaired maturation of bone-forming osteoblasts results in reduced bone formation and subsequent bone weakening, which leads to a number of conditions such as osteogenesis imperfecta (OI). Transplantation of human fetal mesenchymal stem cells has been proposed as skeletal anabolic therapy to enh...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Ranzoni, Anna M., Corcelli, Michelangelo, Hau, Kwan-Leong, Kerns, Jemma G., Vanleene, Maximilien, Shefelbine, Sandra, Jones, Gemma N., Moschidou, Dafni, Dala-Ali, Benan, Goodship, Allen E., De Coppi, Paolo, Arnett, Timothy R., Guillot, Pascale V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171815/
https://ncbi.nlm.nih.gov/pubmed/27995994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39656
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