Upregulating CXCR4 in Human Fetal Mesenchymal Stem Cells Enhances Engraftment and Bone Mechanics in a Mouse Model of Osteogenesis Imperfecta

Stem cells have considerable potential to repair damaged organs and tissues. We previously showed that prenatal transplantation of human first trimester fetal blood mesenchymal stem cells (hfMSCs) in a mouse model of osteogenesis imperfecta (oim mice) led to a phenotypic improvement, with a marked d...

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Detalhes bibliográficos
Main Authors: Jones, Gemma N., Moschidou, Dafni, Lay, Kenneth, Abdulrazzak, Hassan, Vanleene, Maximilien, Shefelbine, Sandra J., Polak, Julia, de Coppi, Paolo, Fisk, Nicholas M., Guillot, Pascale V.
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2012
Assuntos:
Original Articles and Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727689/
https://ncbi.nlm.nih.gov/pubmed/23197643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2011-0007
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