TIARP attenuates autoantibody-mediated arthritis via the suppression of neutrophil migration by reducing CXCL2/CXCR2 and IL-6 expression

TNFα-induced adipose-related protein (TIARP) is a six-transmembrane protein expressed on macrophages, neutrophils and synoviocytes. We reported recently that mice deficient in TIARP (TIARP(−/−)) spontaneously develop arthritis and are highly susceptible to collagen-induced arthritis (CIA) with enhan...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Inoue, Asuka, Matsumoto, Isao, Tanaka, Yuki, Umeda, Naoto, Takai, Chinatsu, Kawaguchi, Hoshimi, Ebe, Hiroshi, Yoshida, Hiroto, Matsumoto, Yoshihiro, Segawa, Seiji, Takahashi, Satoru, Sumida, Takayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171802/
https://ncbi.nlm.nih.gov/pubmed/27995997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38684
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