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Kinetic disruption of lipid rafts is a mechanosensor for phospholipase D

The sensing of physical force, mechanosensation, underlies two of five human senses—touch and hearing. How transduction of force in a membrane occurs remains unclear. We asked if a biological membrane could employ kinetic energy to transduce a signal absent tension. Here we show that lipid rafts are...

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Pubblicato in:Nat Commun
Autori principali: Petersen, E. Nicholas, Chung, Hae-Won, Nayebosadri, Arman, Hansen, Scott B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171650/
https://ncbi.nlm.nih.gov/pubmed/27976674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13873
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