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Phospholipase D promotes Arcanobacterium haemolyticum adhesion via lipid raft remodeling and host cell death following bacterial invasion

BACKGROUND: Arcanobacterium haemolyticum is an emerging bacterial pathogen, causing pharyngitis and more invasive infections. This organism expresses an unusual phospholipase D (PLD), which we propose promotes bacterial pathogenesis through its action on host cell membranes. The pld gene is found on...

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Detalhes bibliográficos
Main Authors: Lucas, Erynn A, Billington, Stephen J, Carlson, Petteri, McGee, David J, Jost, B Helen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978216/
https://ncbi.nlm.nih.gov/pubmed/20973961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-10-270
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