Synthesis and functionalization of protease-activated nanoparticles with tissue plasminogen activator peptides as targeting moiety and diagnostic tool for pancreatic cancer

BACKGROUND: Functionalized nanoparticles (NPs) are one promising tool for detecting specific molecular targets and combine molecular biology and nanotechnology aiming at modern imaging. We aimed at ligand-directed delivery with a suitable target-biomarker to detect early pancreatic ductal adenocarci...

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Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: Dobiasch, Sophie, Szanyi, Szilard, Kjaev, Aleko, Werner, Jens, Strauss, Albert, Weis, Christian, Grenacher, Lars, Kapilov-Buchman, Katya, Israel, Liron-Limor, Lellouche, Jean-Paul, Locatelli, Erica, Franchini, Mauro Comes, Vandooren, Jennifer, Opdenakker, Ghislain, Felix, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5168863/
https://ncbi.nlm.nih.gov/pubmed/27993133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-016-0236-3
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