Colonization of xenograft tumors by oncolytic vaccinia virus (VACV) results in enhanced tumor killing due to the involvement of myeloid cells

BACKGROUND: The mechanisms by which vaccinia virus (VACV) interacts with the innate immune components are complex and involve different mechanisms. iNOS-mediated NO production by myeloid cells is one of the central antiviral mechanisms and this study aims to investigate specifically whether iNOS-med...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Transl Med
Main Authors: Kilinc, Mehmet Okyay, Ehrig, Klaas, Pessian, Maysam, Minev, Boris R., Szalay, Aladar A.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5168712/
https://ncbi.nlm.nih.gov/pubmed/27993141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1096-1
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