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Challenges in Drug Discovery for Neurofibromatosis Type 1-Associated Low-Grade Glioma
Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder that results from germline mutations of the NF1 gene, creating a predisposition to low-grade gliomas (LGGs; pilocytic astrocytoma) in young children. Insufficient data and resources represent major challenges to identifying the best po...
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| Publicado no: | Front Oncol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5167692/ https://ncbi.nlm.nih.gov/pubmed/28066715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00259 |
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