Telomere Shortening Exposes Functions for the Mouse Werner and Bloom Syndrome Genes

The Werner and Bloom syndromes are caused by loss-of-function mutations in WRN and BLM, respectively, which encode the RecQ family DNA helicases WRN and BLM, respectively. Persons with Werner syndrome displays premature aging of the skin, vasculature, reproductive system, and bone, and those with Bl...

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Autores principales: Du, Xiaobing, Shen, Johnny, Kugan, Nishan, Furth, Emma E., Lombard, David B., Cheung, Catherine, Pak, Sally, Luo, Guangbin, Pignolo, Robert J., DePinho, Ronald A., Guarente, Leonard, Johnson, F. Brad
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC516757/
https://ncbi.nlm.nih.gov/pubmed/15367665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.19.8437-8446.2004
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