Proteomic analysis of unbounded cellular compartments: synaptic clefts

Cellular compartments that cannot be biochemically isolated are challenging to characterize. Here we demonstrate the proteomic characterization of the synaptic clefts that exist at both excitatory and inhibitory synapses. Normal brain function relies on the careful balance of these opposing neural c...

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Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Loh, Ken H., Stawski, Philipp S., Draycott, Austin S., Udeshi, Namrata D., Lehrman, Emily K., Wilton, Daniel K., Svinkina, Tanya, Deerinck, Thomas J., Ellisman, Mark H., Stevens, Beth, Carr, Steven A., Ting, Alice Y
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167540/
https://ncbi.nlm.nih.gov/pubmed/27565350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.07.041
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