Cellular FLIP Inhibits β-Catenin Ubiquitylation and Enhances Wnt Signaling

Cellular FLIP (cFLIP) is a close homologue of caspase 8 without caspase activity that inhibits Fas signaling. The cFLIP protein is often expressed in human tumors and is believed to suppress antitumor immune responses involving the Fas system. Here, we report that a long form of cFLIP (cFLIP-L) inhi...

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Detalhes bibliográficos
Main Authors: Naito, Mikihiko, Katayama, Ryohei, Ishioka, Toshiyasu, Suga, Akiko, Takubo, Kohei, Nanjo, Masahiro, Hashimoto, Chizuko, Taira, Masanori, Takada, Shinji, Takada, Ritsuko, Kitagawa, Masatoshi, Matsuzawa, Shu-Ichi, Reed, John C., Tsuruo, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC516746/
https://ncbi.nlm.nih.gov/pubmed/15367663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.19.8418-8427.2004
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