Alternative lengthening of human telomeres is a conservative DNA replication process with features of break‐induced replication

Human malignancies overcome replicative senescence either by activating the reverse‐transcriptase telomerase or by utilizing a homologous recombination‐based mechanism, referred to as alternative lengthening of telomeres (ALT). In budding yeast, ALT exhibits features of break‐induced replication (BI...

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Foilsithe in:EMBO Rep
Main Authors: Roumelioti, Fani‐Marlen, Sotiriou, Sotirios K, Katsini, Vasiliki, Chiourea, Maria, Halazonetis, Thanos D, Gagos, Sarantis
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
Ábhair:
Scientific Reports
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167343/
https://ncbi.nlm.nih.gov/pubmed/27760777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643169
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