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Spatiotemporal imaging of small GTPases activity in live cells

Ras-like small GTPases function as molecular switches and regulate diverse cellular events. To examine the dynamics of signaling requires spatiotemporal visualization of their activity in the cell. Current small GTPase sensors rely on specific effector domains that are available for only a small num...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Voss, Stephanie, Krüger, Dennis M., Koch, Oliver, Wu, Yao-Wen
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167155/
https://ncbi.nlm.nih.gov/pubmed/27911813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613999113
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