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The structure of the catechin-binding site of human sulfotransferase 1A1

We are just beginning to understand the allosteric regulation of the human cytosolic sulfotransferase (SULTs) family—13 disease-relevant enzymes that regulate the activities of hundreds, if not thousands, of signaling small molecules. SULT1A1, the predominant isoform in adult liver, harbors two noni...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Cook, Ian, Wang, Ting, Girvin, Mark, Leyh, Thomas S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167148/
https://ncbi.nlm.nih.gov/pubmed/27911811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613913113
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