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LIS1 Regulates Osteoclastogenesis through Modulation of M-SCF and RANKL Signaling Pathways and CDC42

We have previously reported that depletion of LIS1, a key regulator of microtubules and cytoplasmic dynein motor complex, in osteoclast precursor cells by shRNAs attenuates osteoclastogenesis in vitro. However, the underlying mechanisms remain unclear. In this study, we show that conditional deletio...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Ye, Shiqiao, Fujiwara, Toshifumi, Zhou, Jian, Varughese, Kottayil I, Zhao, Haibo
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166490/
https://ncbi.nlm.nih.gov/pubmed/27994513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.15583
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