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Ubiquitin E3 Ligase LNX2 is Critical for Osteoclastogenesis in vitro by Regulating M-CSF/RANKL Signaling and Notch2
The Notch signaling pathway plays a crucial role in skeletal development and homeostasis by regulating the proliferation and differentiation of osteoblasts and osteoclasts. However, the molecular mechanisms modulating the level and activity of Notch receptors in bone cells remain unknown. In this st...
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| Published in: | Calcif Tissue Int |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4730947/ https://ncbi.nlm.nih.gov/pubmed/25712254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-015-9967-7 |
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