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BMP-2 decreases Mash1 stability by increasing Id1 expression

In neural development, bone morphogenetic proteins (BMPs) restrict neuronal differentiation, thereby promoting the maintenance of progenitor cells or even inducing astrocytogenesis. We report that exposure of neuroendocrine lung carcinoma cells to BMP-2 leads to a rapid decline in steady-state level...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Viñals, Francesc, Reiriz, Julia, Ambrosio, Santiago, Bartrons, Ramon, Rosa, Jose Luis, Ventura, Francesc
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC516632/
https://ncbi.nlm.nih.gov/pubmed/15318167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600360
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