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BMP-2 decreases Mash1 stability by increasing Id1 expression

In neural development, bone morphogenetic proteins (BMPs) restrict neuronal differentiation, thereby promoting the maintenance of progenitor cells or even inducing astrocytogenesis. We report that exposure of neuroendocrine lung carcinoma cells to BMP-2 leads to a rapid decline in steady-state level...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Viñals, Francesc, Reiriz, Julia, Ambrosio, Santiago, Bartrons, Ramon, Rosa, Jose Luis, Ventura, Francesc
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516632/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15318167/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600360
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