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Mss51p and Cox14p jointly regulate mitochondrial Cox1p expression in Saccharomyces cerevisiae

Mutations in SURF1, the human homologue of yeast SHY1, are responsible for Leigh's syndrome, a neuropathy associated with cytochrome oxidase (COX) deficiency. Previous studies of the yeast model of this disease showed that mutant forms of Mss51p, a translational activator of COX1 mRNA, partiall...

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Autors principals: Barrientos, Antoni, Zambrano, Andrea, Tzagoloff, Alexander
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC516630/
https://ncbi.nlm.nih.gov/pubmed/15306853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600358
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