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Lifestyle intervention in BRCA1/2 mutation carriers: study protocol for a prospective, randomized, controlled clinical feasibility trial (LIBRE-1 study)

BACKGROUND: Women with highly penetrant BRCA mutations have a 55–60% lifetime risk for breast cancer and a 16–59% lifetime risk for ovarian cancer. However, penetrance differs interindividually, indicating that environmental and behavioral factors may modify this risk. These include lifestyle factor...

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Dades bibliogràfiques
Publicat a:Pilot Feasibility Stud
Autors principals: Kiechle, Marion, Engel, Christoph, Berling, Anika, Hebestreit, Katrin, Bischoff, Stephan, Dukatz, Ricarda, Gerber, Wolf-Dieter, Siniatchkin, Michael, Pfeifer, Katharina, Grill, Sabine, Yahiaoui-Doktor, Maryam, Kirsch, Ellen, Niederberger, Uwe, Marter, Nicole, Enders, Ute, Löffler, Markus, Meindl, Alfons, Rhiem, Kerstin, Schmutzler, Rita, Erickson, Nicole, Halle, Martin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Study Protocol
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5165708/
https://ncbi.nlm.nih.gov/pubmed/28031860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40814-016-0114-7
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