Precursor fractions of neurotensin and enkephalin might point to molecular mechanisms of cancer risk modulation during a lifestyle-intervention in germline BRCA1/2 gene mutation carriers

BACKGROUND: Germline BRCA1/2 mutation carriers (gBMC) face increased cancer risks that are modulated via non-genetic lifestyle factors whose underlying molecular mechanisms are unknown. The peptides Neurotensin (NT) and Enkephalin (ENK)—involved in tumorigenesis and obesity-related diseases—are of i...

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發表在:Breast Cancer Res Treat
Main Authors: Grill, Sabine, Yahiaoui-Doktor, Maryam, Basrai, Maryam, Struck, Joachim, Schulte, Janin, Berling-Ernst, Anika, Engel, Christoph, Ullrich, Mirjam, Lammert, Jacqueline, Bischoff, Stephan C., Schmidt, Thorsten, Niederberger, Uwe, Chronas, Dimitrios, Rhiem, Kerstin, Schmutzler, Rita, Halle, Martin, Kiechle, Marion
格式: Artigo
語言:Inglês
出版: Springer US 2021
主題:
Clinical Trial
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019429/
https://ncbi.nlm.nih.gov/pubmed/33543354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-020-06070-x
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