Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells

Functional hepatocytes derived from human pluripotent stem cells (hPSCs) have potential as tools for predicting drug-induced hepatotoxicity in the early phases of drug development. However, the propensity of hPSC lines to differentiate into specific lineages is reported to differ. The ability to pre...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Stem Cells Dev
Egile Nagusiak: Yanagihara, Kana, Liu, Yujung, Kanie, Kei, Takayama, Kazuo, Kokunugi, Minako, Hirata, Mitsuhi, Fukuda, Takayuki, Suga, Mika, Nikawa, Hiroki, Mizuguchi, Hiroyuki, Kato, Ryuji, Furue, Miho K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc. 2016
Gaiak:
Original Research Reports
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5165660/
https://ncbi.nlm.nih.gov/pubmed/27733097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2016.0099
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