Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells

Functional hepatocytes derived from human pluripotent stem cells (hPSCs) have potential as tools for predicting drug-induced hepatotoxicity in the early phases of drug development. However, the propensity of hPSC lines to differentiate into specific lineages is reported to differ. The ability to pre...

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Detalhes bibliográficos
Publicado no:Stem Cells Dev
Main Authors: Yanagihara, Kana, Liu, Yujung, Kanie, Kei, Takayama, Kazuo, Kokunugi, Minako, Hirata, Mitsuhi, Fukuda, Takayuki, Suga, Mika, Nikawa, Hiroki, Mizuguchi, Hiroyuki, Kato, Ryuji, Furue, Miho K.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5165660/
https://ncbi.nlm.nih.gov/pubmed/27733097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2016.0099
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