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Tetra-O-methyl nordihydroguaiaretic acid induces growth arrest and cellular apoptosis by inhibiting Cdc2 and survivin expression

We previously reported that Sp1-dependent Cdc2 gene expression is inhibited by tetra-O-methyl nordihydroguaiaretic acid (M(4)N) and that M(4)N is likely responsible for causing growth arrest in M(4)N-treated transformed C3 cells. Here, we show that after M(4)N treatment and cell-cycle arrest, expres...

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Bibliographische Detailangaben
Hauptverfasser: Chang, Chih-Chuan, Heller, Jonathan D., Kuo, Jennifer, Huang, Ru Chih C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC516554/
https://ncbi.nlm.nih.gov/pubmed/15329416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405407101
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