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Dysregulated Glycoprotein B-Mediated Cell-Cell Fusion Disrupts Varicella-Zoster Virus and Host Gene Transcription during Infection

The highly conserved herpesvirus glycoprotein complex gB/gH-gL mediates membrane fusion during virion entry and cell-cell fusion. Varicella-zoster virus (VZV) characteristically forms multinucleated cells, or syncytia, during the infection of human tissues, but little is known about this process. Th...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Oliver, Stefan L., Yang, Edward, Arvin, Ann M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5165202/
https://ncbi.nlm.nih.gov/pubmed/27795423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01613-16
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