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Dysregulated Glycoprotein B-Mediated Cell-Cell Fusion Disrupts Varicella-Zoster Virus and Host Gene Transcription during Infection

The highly conserved herpesvirus glycoprotein complex gB/gH-gL mediates membrane fusion during virion entry and cell-cell fusion. Varicella-zoster virus (VZV) characteristically forms multinucleated cells, or syncytia, during the infection of human tissues, but little is known about this process. Th...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Oliver, Stefan L., Yang, Edward, Arvin, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5165202/
https://ncbi.nlm.nih.gov/pubmed/27795423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01613-16
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